| Heim | Gast | Ergebnis | Spieltag | Datum |
|---|---|---|---|---|
| CS Brügge | FC Seraing | 2:0 | 19 | 14.12.21 - 18:45 Uhr |
| KV Oostende | KV Kortrijk | 0:2 | 19 | 14.12.21 - 21:00 Uhr |
| Anderlecht | Sint-Truiden | 2:0 | 19 | 14.12.21 - 21:00 Uhr |
| KV Mechelen | AA Gent | 4:2 | 19 | 15.12.21 - 18:45 Uhr |
| Zulte-Wareg. | Union St-Gill. | 0:2 | 19 | 15.12.21 - 18:45 Uhr |
| Standard | Beerschot | ausg. | 19 | 15.12.21 - 21:00 Uhr |
| OH Löwen | Club Brügge | 1:4 | 19 | 15.12.21 - 21:00 Uhr |
| Antwerp | AS Eupen | 4:2 | 19 | 16.12.21 - 18:45 Uhr |
| KRC Genk | Charleroi | 4:2 | 19 | 16.12.21 - 21:00 Uhr |
| P | Verein | Sp. | S | U | N | Tore | Diff. | Pkt. |
|---|---|---|---|---|---|---|---|---|
| 1 | Union St-Gill. | 19 | 14 | 1 | 4 | 47:18 | 29 | 43 |
| 2 | Club Brügge | 19 | 11 | 6 | 2 | 39:24 | 15 | 39 |
| 3 | Antwerp | 19 | 11 | 3 | 5 | 36:23 | 13 | 36 |
| 4 | Anderlecht | 19 | 9 | 7 | 3 | 41:24 | 17 | 34 |
| 5 | Charleroi | 19 | 9 | 5 | 5 | 34:26 | 8 | 32 |
| 6 | AA Gent | 19 | 9 | 3 | 7 | 30:21 | 9 | 30 |
| 7 | KV Mechelen | 19 | 9 | 3 | 7 | 33:33 | 0 | 30 |
| 8 | KV Kortrijk | 19 | 7 | 7 | 5 | 24:22 | 2 | 28 |
| 9 | KRC Genk | 19 | 7 | 4 | 8 | 35:32 | 3 | 25 |
| 10 | AS Eupen | 19 | 7 | 4 | 8 | 30:30 | 0 | 25 |
| 11 | Standard | 18 | 6 | 5 | 7 | 21:31 | -10 | 23 |
| 12 | CS Brügge | 19 | 6 | 4 | 9 | 24:25 | -1 | 22 |
| 13 | Sint-Truiden | 19 | 6 | 3 | 10 | 19:29 | -10 | 21 |
| 14 | KV Oostende | 19 | 6 | 2 | 11 | 21:39 | -18 | 20 |
| 15 | OH Löwen | 19 | 4 | 8 | 7 | 24:33 | -9 | 20 |
| 16 | FC Seraing | 19 | 6 | 1 | 12 | 23:38 | -15 | 19 |
| 17 | Zulte-Wareg. | 19 | 4 | 5 | 10 | 27:43 | -16 | 17 |
| 18 | Beerschot | 18 | 2 | 3 | 13 | 15:32 | -17 | 9 |
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